Cardiovascular Disease
When the inner section of the coronary arteries become partially or completely occluded, some areas of the heart fail to receive the irrigation needs (ischemia). The main symptom is chest pain that may radiate to the neck and left arm. If the injury is partial, the result is angina, a condition that leaves no sequelae. By contrast, total occlusion of an artery may cause necrosis (death) from heart muscle and is called myocardial infarction. The affected area loses its contractile function.
other hand along life, an artery experiences a natural degenerative process, with narrowing of the inner section and progressive increase in wall thickness. The large blood vessels, especially the aorta, may have abnormal dilation, called aneurysms, usually caused by atherosclerotic plaques, which are deposits of cholesterol and other various substances on the inner walls of the arteries. The increased thickness of plaque narrows the inside section of blood vessel and may produce stroke. Atherosclerosis in this degenerative process is compounded because the disease causes hardening of the arteries and loss of elasticity.
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